Recombinant SARS-CoV-2 Proteins
To support COVID-19 research, we produce recombinant SARS-CoV-2 proteins which can be used as antigen or control protein for analytic and diagnostic purposes as well as for vaccine development.
As most important surface membrane protein for Coronavirus research, the recombinant protein of the receptor binding domain (RBD) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus can be delivered off-the shelf. Furthermore, the human cell surface receptor Angiotensin-Converting Enzyme 2 (ACE-2), binding to the RBD of SARS-CoV-2 Spike S1, and the SARS-CoV-2 Proteinase 3 CL-Mpro (His-Tag or Tag-free), which controls the activities of the coronavirus replication complex, can be ordered from stock.
Our R&D is continuously working with high priority on producing further relevant recombinant SARS-CoV-2 proteins for COVID-19 research like: Spike Glycoproteins S1 and S2 as different variants, the Nucleocapsid Protein and other important Coronavirus proteins.
If you want to discuss your planned COVID-19 research project directly with our scientific experts or if you have any customized inquiries or suggestions for SARS-CoV-2 related protein development, please do not hesitate to contact us.
Background to the new Coronavirus SARS-CoV-2
The spread of the 2019 new Coronavirus (SARS-CoV-2) throughout the world has a strong impact on our daily life and the fight against COVID-19 is one of the most important tasks of the scientific world in these days.
The new Coronavirus (SARS-CoV-2) belongs to a group of enveloped positive-stranded RNA viruses that consist of four structural proteins including spike (S) glycoprotein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein.
As the most important surface protein of SARS-CoV-2, the Spike glycoprotein can mediate the infection of human respiratory epithelial cells by binding the cell surface receptor angiotensin-converting enzyme 2 (ACE2).
Fig.1: Protein structure of new Coronavirus (SARS-CoV-2): Spike (S) Glycoprotein, Envelope protein (E), Membrane protein (M) and Nucleocapsid protein (N)
Catalog of Recombinant SARS-CoV-2 Proteins
|Protein Name||Species||Expression Host||Catalog No.||Data sheet||Availability|
|SARS-CoV-2 (COVID-19) Spike S1 Protein (RBD), His-Tag||SARS-CoV-2; Wuhan seafood market pneumonia virus||human, HEK293||P2020-001|
|Human ACE2 Protein (ECD, processed), Tag-free||Homo sapiens, human||human, HEK293||P2020-016|
|SARS-CoV-2 (COVID-19) 3CL-Mpro Protein, His-Tag||SARS-CoV-2; Wuhan seafood market pneumonia virus||E. coli||P2020-018|
|SARS-CoV-2 (COVID-19) 3CL-Mpro Protein, Tag-free||SARS-CoV-2; Wuhan seafood market pneumonia virus||E. coli||P2020-019|
|SARS-CoV-2 (COVID-19) Spike S protein (ECD), Fc-Tag||SARS-CoV-2; Wuhan seafood market pneumonia virus||human, HEK293||P2020-005|
|SARS-CoV-2 (COVID-19) Spike S1 protein, His-Tag||SARS-CoV-2; Wuhan seafood market pneumonia virus||human, HEK293||P2020-006|
|SARS-CoV-2 (COVID-19) Nucleocapsid protein, His-Tag||SARS-CoV-2; Wuhan seafood market pneumonia virus||E. coli||P2020-010|
|Human ACE2 Protein (ECD), Avi-Tag||Homo sapiens, human||human, HEK293||P2020-017|
Further off-the-shelf recombinant proteins
Learn more about our other off-the-shelf recombinant proteins in our continuously growing catalog.
Reinhold Horlacher, PhD
Managing Director & CSO
We would be happy to provide you with support on your protein research project. Let us know your questions and requests, our scientific experts will reply shortly.
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