Recombinant SARS-CoV-2 Proteins

To support COVID-19 research, we produce recombinant SARS-CoV-2 proteins which can be used as antigen or control protein for analytic and diagnostic purposes as well as for vaccine development.

As most important surface membrane protein for Coronavirus research, the recombinant protein of the receptor binding domain (RBD) of SARS-CoV-2 (COVID-2019) Spike S1 from Wuhan pneumonia virus can be delivered off-the shelf. Furthermore, the human cell surface receptor Angiotensin-Converting Enzyme 2 (ACE-2), binding to the RBD of SARS-CoV-2 Spike S1, and the SARS-CoV-2 Proteinase 3 CL-Mpro (His-Tag or Tag-free), which controls the activities of the coronavirus replication complex, can be ordered from stock.

Our R&D is continuously working with high priority on producing further relevant recombinant SARS-CoV-2 proteins for COVID-19 research like: Spike Glycoproteins S1 and S2 as different variants, the Nucleocapsid Protein and other important Coronavirus proteins.

If you want to discuss your planned COVID-19 research project directly with our scientific experts or if you have any customized inquiries or suggestions for SARS-CoV-2 related protein development, please do not hesitate to contact us.

Background to the new Coronavirus SARS-CoV-2

The spread of the 2019 new Coronavirus (SARS-CoV-2) throughout the world has a strong impact on our daily life and the fight against COVID-19 is one of the most important tasks of the scientific world in these days.

The new Coronavirus (SARS-CoV-2) belongs to a group of enveloped positive-stranded RNA viruses that consist of four structural proteins including spike (S) glycoprotein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein.

As the most important surface protein of SARS-CoV-2, the Spike glycoprotein can mediate the infection of human respiratory epithelial cells by binding the cell surface receptor angiotensin-converting enzyme 2 (ACE2).

 

Fig.1: Protein structure of new Coronavirus (SARS-CoV-2): Spike (S) Glycoprotein, Envelope protein (E), Membrane protein (M) and Nucleocapsid protein (N)

Catalog of Recombinant SARS-CoV-2 Proteins

Protein NameSpeciesExpression HostCatalog No.Data sheetAvailability
SARS-CoV-2 (COVID-19) Spike S1 Protein (RBD), His-TagSARS-CoV-2; Wuhan seafood market pneumonia virushuman, HEK293P2020-001 Button Get a quote
Human ACE2 Protein (ECD, processed), Tag-freeHomo sapiens, humanhuman, HEK293P2020-016 Button Get a quote
SARS-CoV-2 (COVID-19) 3CL-Mpro Protein, His-TagSARS-CoV-2; Wuhan seafood market pneumonia virusE. coliP2020-018 Button Get a quote
SARS-CoV-2 (COVID-19) 3CL-Mpro Protein, Tag-freeSARS-CoV-2; Wuhan seafood market pneumonia virusE. coliP2020-019 Button Get a quote
SARS-CoV-2 (COVID-19) Spike S protein (ECD), Fc-TagSARS-CoV-2; Wuhan seafood market pneumonia virushuman, HEK293P2020-005Button Coming soon
SARS-CoV-2 (COVID-19) Spike S1 protein, His-TagSARS-CoV-2; Wuhan seafood market pneumonia virushuman, HEK293P2020-006 Button Coming soon
SARS-CoV-2 (COVID-19) Nucleocapsid protein, His-TagSARS-CoV-2; Wuhan seafood market pneumonia virusE. coliP2020-010Button Coming soon
Human ACE2 Protein (ECD), Avi-TagHomo sapiens, humanhuman, HEK293P2020-017Button Coming soon

Further off-the-shelf recombinant proteins

Learn more about our other off-the-shelf recombinant proteins in our continuously growing catalog.

Reinhold Horlacher, PhD

Reinhold Horlacher, PhD

Managing Director & CSO

We would be happy to provide you with support on your protein research project. Let us know your questions and requests, our scientific experts will reply shortly.

Get In Contact With Our Scientific Experts





Catalog Protein*

Desired Quantity*


By submitting this form, I consent to trenzyme GmbH receiving and processing my data in order to process my inquiry. My consent is voluntary and I may revoke this consent at any time without providing any reasons, e.g. by sending an email to privacy(at)trenzyme.com with effect for the future. Further notices on data processing can be found in our privacy policy.